EXPLORATION OF THE EFFICACY AND SAFETY OF ORAL MOISTURIZING AGENTS FOR DRY MOUTH AND XEROSTOMIA: A SYSTEMATIC REVIEW

This systematic review aimed to explore the efficacy and safety of oral moisturizing agents for dry mouth xerostomia. Oral improve patient's quality life by mucosa maintaining buffer capacity. The methods this was structured following Preferred Reporting Items Systematic Reviews Meta-Analyses (PRISMA) guidelines. Pubmed Ebscohost-CINAHL Plus databases were used article searching. JADAD or Oxford scoring system assess risk bias. tested moisturizer mouthwash, Verramin gel, jelly (OMJ), GC Dry Mouth Gel®, aloe vera ginger mouthwash. All them can reduce discomfort complaints in patients. Even OMJ could increase salivary pH candidiasis. There no significant difference after using mouthwash patients with Sjogren's syndrome compared giving natural water as a control. Mild moderate adverse effects found due use overcome problem effectively safely xerostomia, however, less effective syndrome.